Clinical Trials Related to Endocrinology
Endocrinology is the study of medicine that relates to the endocrine system – the system that controls hormones and the glands which release them. Endocrinologists treat people who suffer from hormone imbalances with the goal to restore normal balance to these hormones. Aging, stress, environmental factors, and disease can affect the hormone balance in your body. Hormone imbalance can lead to chronic kidney disease, diabetes, high cholesterol, thyroid disease, as well as cancer.
Participate in a clinical trial to help find alternative treatment options for different endocrinology conditions.
Diabetes Type 1
Pediatric Type 1 diabetes is a type of diabetes which affects children and young people. This form of diabetes happens when the body doesn’t produce enough insulin, a hormone that helps glucose get into cells to energize them. Without sufficient insulin, the body doesn’t have enough energy and glucose builds up in the bloodstream instead of going into cells. Symptoms include excessive thirst, frequent urination and unexplained weight loss.
Type 2 Diabetes
Diabetes mellitus type 2 is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, and unexplained weight loss. Symptoms may also include increased hunger, feeling tired, and sores that do not heal. Often symptoms come on slowly. Long-term complications from high blood sugar include heart disease, strokes, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to amputations.
Diabetic Peripheral Neuropathy (DPN) PAIN
Diabetic peripheral neuropathies are nerve-damaging disorders associated with diabetes mellitus. These conditions are thought to result from a diabetic microvascular injury involving small blood vessels that supply nerves (vasa nervorum) in addition to macrovascular conditions that can accumulate in diabetic neuropathy.
When you eat, your body converts any calories it doesn’t need to use right away into triglycerides. These triglycerides are stored in your fat cells. If you eat more calories than you burn, you may have high triglycerides (hypertriglyceridemia).
Cholesterol is a waxy substance found in your blood. Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. With high cholesterol, you can develop fatty deposits in your blood vessels. Eventually, these deposits grow, making it difficult for enough blood to flow through your arteries. Sometimes, those deposits can break suddenly and form a clot that causes a heart attack or stroke.
Obesity is a complicated condition characterized by an excess of body fat. Obesity is more than simply an aesthetic issue. It is a medical condition that raises the risk of developing other diseases and health issues, such as heart disease, diabetes, high blood pressure, and some malignancies.
Diabetic Foot Ulcers
Foot Ulcers are a typical consequence of diabetes that is not treated with diet, exercise, or insulin administration. Ulcers are caused by skin tissue breaking down and exposing the layers beneath.
A significant foot ulcer is distinguished by the presence of black tissue (called eschar) surrounding the lesion. This occurs due to a lack of good blood flow to the area around the ulcer.
Hyperthyroidism happens when the thyroid gland makes too much thyroid hormone. This condition also is called overactive thyroid. Hyperthyroidism speeds up the body’s metabolism. That can cause many symptoms, such as weight loss, hand tremors, and rapid or irregular heartbeat. Sometimes, hyperthyroidism treatment includes surgery to remove all or part of the thyroid gland. In some cases, depending on what’s causing it, hyperthyroidism may improve without medication or other treatment.
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